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Extensive in vitro pharmacological characterization of the active peptides revealed that P5 displayed comparable efficacy to the endogenous ligand GLP-1 and its analogue Ex4 with regards to G-protein signalling

The demand for GLP-1 drugs will grow, and at a potentially substantial rate, if manufacturers obtain FDA-approval for treating nonalcoholic fatty liver disease, polycystic ovary syndrome, sleep apnea, diabetes prevention and other benefits without new serious adverse effects, Patrick Gleason, assistant vice president for Health Outcomes at Prime Therapeutics and Magellan Rx, a pharmacy benefits management company, told BioSpace in an email.

Hiccups are considered an uncommon or rare potential side effect based on current patient reports

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